HPLC Column, RP PFP, 3um, 4.0mm ID x 100mm Length, 100A. Cogent Brand. 1 EA. CUSTOM ORDER.
Additional Info:
The 68322‑10P‑4 Cogent RP PFP™ HPLC Column is designed for enhanced selectivity of halogenated, aromatic, and polar compounds, delivering improved resolution where traditional C18 phases may not fully separate structurally similar analytes.
This stationary phase incorporates a pentafluorophenyl (PFP, “F5”) ligand bonded via a four‑carbon linker to high‑purity silica with full double end‑capping, enabling multiple interaction mechanisms including π‑π interactions, dipole interactions, and hydrogen bonding. These combined interactions provide greater selectivity control and improved separation performance.
The 100 Å pore size offers balanced versatility, supporting both small and moderately sized molecules in analytical workflows.
100 mm Length – Increased Resolution for Analytical Methods
The 100 mm length provides a balance between speed and resolving power, improving separation compared to shorter columns while maintaining efficient run times.
Better resolution than 50 mm screening columns
Improved separation of closely related compounds
Increased peak capacity for complex mixtures
✅ Use when additional resolution is required without extending to 150 mm columns
Flow Rate & System Requirements (4.0 mm ID, 3 µm)
⚠️ Compatible with standard HPLC systems, with moderate backpressure
Typical flow rate range: ~0.8–1.5 mL/min
Higher efficiency than 5 µm columns
Increased backpressure relative to larger particles
Suitable for standard analytical detectors
✅ Sample preparation requirement: filter samples using a 0.2 µm syringe filter prior to injection
Why Choose PFP (F5) for Selective Separations
Enhanced Retention for Halogenated Compounds
Strong interaction with fluorinated and halogenated analytes
Improved selectivity vs C18
Multiple Interaction Mechanisms
π‑π interactions for aromatic compounds
Dipole and hydrogen bonding interactions
Greater flexibility in method development
Balanced 100 Å Pore Structure
Suitable for a wide range of analyte sizes
Consistent performance across applications
Cogent RP PFP™ Advantages
Fully End‑Capped Surface
Minimizes silanol activity
Improves peak symmetry
High Efficiency (3 µm Particles)
Higher efficiency than 5 µm columns
Sharper peaks and improved resolution
High Purity Silica
Consistent chromatographic performance
Reliable reproducibility across runs
Typical Applications
Halogenated compound analysis
Aromatic compound separations
Pharmaceutical analytical workflows
Method development and refinement
USP L43 method applications
Important Usage Notes
Packed and shipped in reversed‑phase solvents
Designed for standard analytical HPLC systems (4.0 mm ID)
Higher backpressure than larger particle sizes
👉 Made‑to‑Order Columns & Pricing Information
This is a custom, made‑to‑order column.
Columns are manufactured specifically to order
Orders cannot be canceled once placed
Custom columns are non‑returnable